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Immune Builder

Design Antibodies, Nanobodies, and T-Cell Receptors using Immune Builder's state-of-the-art generative models.

Overview

Leverage Immune Builder's AbodyBuilder 2, NanoBodyBuilder 2, and TCRBuilder 2 models to generate Antibodies, Nanobodies, and T-Cell Receptors with more accuracy than AlphaFold and signifcantly faster inference than competing models.

Run Immune Builder on Neurosnap

The Immune Builder online webserver allows anybody with a Neurosnap account to run and access Immune Builder, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.

Immune Builder service preview

Features

  • Design Antibodies, Nanobodies, and T-Cell Receptors from sequences.
  • Performs refinement steps using OpenMM.
  • Returns PDB files and confidence metrics.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access Immune Builder using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Citations

Please cite the original work when using Immune Builder in publications or research outputs.

Abanades, B. et al., ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins, https://www.nature.com, 29 May 2023, https://www.nature.com/articles/s42003-023-04927-7.

Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/

Set up your run

Configure Immune Builder

Choose your inputs and settings, then review the estimated credits before submitting.

Use a note to recognize this job later. It does not affect the results.

Inputs & configuration

Loading inputs and options... validating knobs, tuning dials, and staging your experiment.

Ready to submit your job?

Review your configuration, then confirm the estimated credit cost before you run the job.

Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.

Estimated Credits: calculating...

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